Researchers have revealed that so-called “junk DNA” contains powerful switches that help control brain cells linked to Alzheimer’s disease. By experimentally testing nearly 1,000 DNA switches in human ...
Gene expression analysis and RNA sequencing have transformed our understanding of molecular biology, offering a comprehensive view of transcriptomic landscapes in diverse biological systems. By ...
DNA is transcribed into RNA, which is then translated into proteins. This is the central dogma of molecular biology – a mantra taught to every biology undergraduate student to be recalled and expanded ...
Our genes contain all the instructions our body needs to function, but their expression must be finely regulated to guarantee that each cell performs its role optimally. This is where DNA and RNA ...
Gene dysregulation is a hallmark of disease, driving pathogenic phenotypes and poor patient outcomes. RNA binding proteins are often important human gene effectors, controlling RNA synthesis, ...
Gene editing is now reaching the mainstream, ushering in a new era of genetic manipulation. Traditionally, inserting or deleting entire genes, regulating their expression, and altering specific ...
Collaboration to leverage CAMP4’s RAP Platform® to accelerate development of novel antisense oligonucleotides (ASOs) for neurodegenerative and renal diseases CAMP4 to receive $17.5 million upfront and ...
SMRTS, a smart mRNA system, enables cell‑selective gene expression, expanding the mRNA toolbox for precision cancer therapies.
Liquid culture flasks of bacteria grown in yellow broth covered with tinfoil on a shaker. Bacterial strains needed to be tested every step of the way to create the highly compressed genome. Credit: ...
In the microscopic world of bacteria, gene transfer is a powerful mechanism that can alter cellular function, drive antibiotic resistance and even shape entire ecosystems. Now an interdisciplinary ...
The authors do not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and have disclosed no relevant affiliations beyond their ...